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Covalent fragment-based drug discovery workflow demonstrated on Bruton’s Tyrosine Kinase
A Medicinal Chemistry Strategy for DEL-Hit Optimization and Identification of New Ligase Warheads for Targeted Protein Degradation
A Semi-Automated Chromatography Platform for Parallel Purification of High Quality Therapeutic Targets
Integrated Screening in Hit-Identification - Combining DEL-Hit Results with FBDD and Computational Approaches
Structural Insights into a Cas9 Ortholog by Cryo-EM & X-ray Crystallography
Library Design and Screening Strategies to Enable Informed DEL Screening - A Toolbox for Integrated Screening Approaches
Advancing Drug Discovery for Membrane Proteins
A Comprehensive Structural Biology Platform for Structure-Based Drug Discovery
A Streamlined Drug Discovery Platform for the Production and Characterization of Protein Biologics and Their Antigens